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If it can be, and if the JNK path is essential for viral reactivation in human beings, then it could be possible to establish treatments for the diseases that are linked to HSV, along with its closely-related infections. This approach was nearly as efficient at providing the siRNAs to the cells as the lipid transfection procedure and protected the mice longer.
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One reason is the ability of latent virus to continue cells and re-emerge in reaction to imperfectly comprehended stimuli. When challenged with the HSV-2 virus for up to one week after being given the siRNA, the cured mice were still safeguarded. National Health and Nutrition Assessment Survey.
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